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Structural Mechanism of Cooperative Regulation of Calcium-Sensing Receptor-Mediated Cellular Signaling

Calcaium sensing receptors (CaSRs) play a central role in regulating extracellular calcium (Ca(2+)) homeostasis and many (patho)physiological processes. This regulation is primarily orchestrated in response to extracellular stimuli via the extracellular domain (ECD). This paper first reviews the mod...

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Detalhes bibliográficos
Publicado no:Curr Opin Physiol
Main Authors: Deng, Xiaonan, Xin, Yao, Miller, Cassandra Lynn, Hamelberg, Donald, Kirberger, Michael, Moremen, Kelley W., Hu, Jian, Yang, Jenny J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943033/
https://ncbi.nlm.nih.gov/pubmed/33709045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cophys.2020.08.020
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