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Control of Vascular Permeability by Atrial Natriuretic Peptide via a GEF-H1-dependent Mechanism
Microtubule (MT) dynamics is involved in a variety of cell functions, including control of the endothelial cell (EC) barrier. Release of Rho-specific nucleotide exchange factor GEF-H1 from microtubules activates the Rho pathway of EC permeability. In turn, pathologic vascular leak can be prevented b...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931074/ https://ncbi.nlm.nih.gov/pubmed/24352660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493924 |
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