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Control of Vascular Permeability by Atrial Natriuretic Peptide via a GEF-H1-dependent Mechanism

Microtubule (MT) dynamics is involved in a variety of cell functions, including control of the endothelial cell (EC) barrier. Release of Rho-specific nucleotide exchange factor GEF-H1 from microtubules activates the Rho pathway of EC permeability. In turn, pathologic vascular leak can be prevented b...

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Autori principali: Tian, Xinyong, Tian, Yufeng, Gawlak, Grzegorz, Sarich, Nicolene, Wu, Tinghuai, Birukova, Anna A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931074/
https://ncbi.nlm.nih.gov/pubmed/24352660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493924
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