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Mutations in the Chromodomain-like Insertion of Translation Elongation Factor 3 Compromise Protein Synthesis through Reduced ATPase Activity

Translation elongation is mediated by ribosomes and multiple soluble factors, many of which are conserved across bacteria and eukaryotes. During elongation, eukaryotic elongation factor 1A (eEF1A; EF-Tu in bacteria) delivers aminoacylated-tRNA to the A-site of the ribosome, whereas eEF2 (EF-G in bac...

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Bibliografiska uppgifter
Huvudupphovsmän: Sasikumar, Arjun N., Kinzy, Terri Goss
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931047/
https://ncbi.nlm.nih.gov/pubmed/24379402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536201
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