Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice

BACKGROUND: Methylation on the fifth position of cytosine (5-mC) is an essential epigenetic mark that is linked to both normal neurodevelopment and neurological diseases. The recent identification of another modified form of cytosine, 5-hydroxymethylcytosine (5-hmC), in both stem cells and post-mito...

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Autori principali: Chopra, Pankaj, Papale, Ligia A, White, Andrew T J, Hatch, Andrea, Brown, Ryan M, Garthwaite, Mark A, Roseboom, Patrick H, Golos, Thaddeus G, Warren, Stephen T, Alisch, Reid S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Methodology Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930898/
https://ncbi.nlm.nih.gov/pubmed/24524199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-131
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