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Species-Specific 5 mC and 5 hmC Genomic Landscapes Indicate Epigenetic Contribution to Human Brain Evolution

Human evolution from non-human primates has seen substantial change in the central nervous system, with the molecular mechanisms underlying human brain evolution remaining largely unknown. Methylation of cytosine at the fifth carbon (5-methylcytosine; 5 mC) is an essential epigenetic mark linked to...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Madrid, Andy, Chopra, Pankaj, Alisch, Reid S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817089/
https://ncbi.nlm.nih.gov/pubmed/29491831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00039
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