5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

DNA methylation dynamics influence brain function and are altered in neurological disorders. 5-hydroxymethylcytosine (5-hmC), a DNA base that is derived from 5-methylcytosine, accounts for ~40% of modified cytosine in the brain and has been implicated in DNA methylation–related plasticity. We mapped...

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Hauptverfasser: Szulwach, Keith E, Li, Xuekun, Li, Yujing, Song, Chun-Xiao, Wu, Hao, Dai, Qing, Irier, Hasan, Upadhyay, Anup K, Gearing, Marla, Levey, Allan I, Vasanthakumar, Aparna, Godley, Lucy A, Chang, Qiang, Cheng, Xiaodong, He, Chuan, Jin, Peng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292193/
https://ncbi.nlm.nih.gov/pubmed/22037496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2959
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