Positive Regulation of TRAF6-Dependent Innate Immune Responses by Protein Phosphatase PP1-γ

Innate immune sensors such as Toll-like receptors (TLRs) differentially utilize adaptor proteins and additional molecular mediators to ensure robust and precise immune responses to pathogen challenge. Through a gain-of-function genetic screen, we identified the gamma catalytic subunit of protein pho...

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Главные авторы: Opaluch, Amanda M., Schneider, Monika, Chiang, Chih-yuan, Nguyen, Quy T., Maestre, Ana M., Mulder, Lubbertus C. F., Secundino, Ismael, De Jesus, Paul D., König, Renate, Simon, Viviana, Nizet, Victor, MacLeod, Graham, Varmuza, Susannah, Fernandez-Sesma, Ana, Chanda, Sumit K.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930702/
https://ncbi.nlm.nih.gov/pubmed/24586659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089284
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