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Co-factors Required for TLR7- and TLR9- dependent Innate Immune Responses
Pathogens commonly utilize endocytic pathways to gain cellular access. The endosomal pattern recognition receptors TLR7 and TLR9 detect pathogen-encoded nucleic acids to initiate MyD88-dependent pro-inflammatory responses to microbial infection. Using genome-wide RNAi screening and integrative syste...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310399/ https://ncbi.nlm.nih.gov/pubmed/22423970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.02.002 |
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