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Inflammation Enhances IL-2 Driven Differentiation of Cytolytic CD4 T Cells

Cytolytic CD4 T cells (CD4 CTL) have been identified in vivo in response to viral infections; however, the factors necessary for driving the cytolytic phenotype have not been fully elucidated. Our previously published work suggests IL-2 may be the master regulator of perforin-mediated cytotoxicity i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Workman, Aspen M., Jacobs, Ashley K., Vogel, Alexander J., Condon, Shirley, Brown, Deborah M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930678/
https://ncbi.nlm.nih.gov/pubmed/24586481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089010
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