IL-4 receptor dependent expansion of lung CD169(+) macrophages in microfilaria-driven inflammation

Lung disease is regularly reported in human filarial infections but the molecular pathogenesis of pulmonary filariasis is poorly understood. We used Litomosoides sigmodontis, a rodent filaria residing in the pleural cavity responsible for pleural inflammation, to model responses to human filarial in...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Fercoq, Frédéric, Remion, Estelle, Frohberger, Stefan J., Vallarino-Lhermitte, Nathaly, Hoerauf, Achim, Le Quesne, John, Landmann, Frédéric, Hübner, Marc P., Carlin, Leo M., Martin, Coralie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742411/
https://ncbi.nlm.nih.gov/pubmed/31469835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007691
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