Chemical synthesis of genes for human insulin.

A rapid chemical procedure has been developed and used for the synthesis of 29 oligodeoxyribonucleotides to build synthetic genes for human insulin. The gene for insulin B chain, 104 base pairs, and the one for A chain, 77 base pairs, were designed from the amino acid sequence of human polypeptides....

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Bibliographic Details
Main Authors: Crea, R, Kraszewski, A, Hirose, T, Itakura, K
Format: Artigo
Language:Inglês
Published: 1978
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC393054/
https://ncbi.nlm.nih.gov/pubmed/282602
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