Generation of orthotopic patient-derived xenografts from gastrointestinal stromal tumor

BACKGROUND: Gastrointestinal stromal tumor (GIST) is the most common sarcoma and its treatment with imatinib has served as the paradigm for developing targeted anti-cancer therapies. Despite this success, imatinib-resistance has emerged as a major problem and therefore, the clinical efficacy of othe...

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Detalhes bibliográficos
Main Authors: Sicklick, Jason K, Leonard, Stephanie Y, Babicky, Michele L, Tang, Chih-Min, Mose, Evangeline S, French, Randall P, Jaquish, Dawn V, Hoh, Carl K, Peterson, Michael, Schwab, Richard, Lowy, Andrew M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930355/
https://ncbi.nlm.nih.gov/pubmed/24507750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-41
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