Brain Tumor Initiating Cells Adapt to Restricted Nutrition through Preferential Glucose Uptake

Like all cancers, brain tumors require a continuous source of energy and molecular resources for new cell production. In normal brain, glucose is an essential neuronal fuel, but the blood-brain barrier limits its delivery. We now report that nutrient restriction contributes to tumor progression by e...

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Hlavní autoři: Flavahan, William A., Wu, Qiulian, Hitomi, Masahiro, Rahim, Nasiha, Kim, Youngmi, Sloan, Andrew E., Weil, Robert J., Nakano, Ichiro, Sarkaria, Jann N., Stringer, Brett W., Day, Bryan W., Li, Meizhang, Lathia, Justin D., Rich, Jeremy N., Hjelmeland, Anita B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930177/
https://ncbi.nlm.nih.gov/pubmed/23995067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3510
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