Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity

Growth factor-mediated proliferation and self-renewal maintain tissue-specific stem cells and are frequently dysregulated in cancers. Platelet-derived growth factor (PDGF) ligands and receptors (PDGFRs) are commonly overexpressed in gliomas and initiate tumors, as proven in genetically engineered mo...

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Detalhes bibliográficos
Main Authors: Kim, Youngmi, Kim, Eunhee, Wu, Qiulian, Guryanova, Olga, Hitomi, Masahiro, Lathia, Justin D., Serwanski, David, Sloan, Andrew E., Weil, Robert J., Lee, Jeongwu, Nishiyama, Akiko, Bao, Shideng, Hjelmeland, Anita B., Rich, Jeremy N.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371412/
https://ncbi.nlm.nih.gov/pubmed/22661233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.193565.112
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