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Nucleotide and partner-protein control of bacterial replicative helicase structure and function

Cellular replication forks are powered by ring-shaped, hexameric helicases that encircle and unwind DNA. To better understand the molecular mechanisms and control of these enzymes, we used multiple methods to investigate the bacterial replicative helicase, DnaB. A 3.3 Å crystal structure of Aquifex...

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Detalhes bibliográficos
Main Authors: Strycharska, Melania S., Arias-Palomo, Ernesto, Lyubimov, Artem Y., Erzberger, Jan P., O’Shea, Valerie, Bustamante, Carlos J., Berger, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929961/
https://ncbi.nlm.nih.gov/pubmed/24373746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.11.016
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