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Nanoemulsion mucosal adjuvant uniquely activates cytokine production by nasal ciliated epithelium and induces dendritic cells trafficking

While the nasal mucosa is a potentially useful site for human immunization, toxin-based nasal adjuvants are generally unsafe and less effective in humans. Safe mucosal adjuvants that activate protective immunity via mucosal administration are highly dependent on barrier antigen sampling by epithelia...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Makidon, Paul E., Belyakov, Igor M., Janczak, Katarzyna W., Landers, Jeffrey, Bielinska, Anna U., Groom, Jeffrey V., Baker, James R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929939/
https://ncbi.nlm.nih.gov/pubmed/22653620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142346
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