Distinct Pathways of Humoral and Cellular Immunity Induced with the Mucosal Administration of a Nanoemulsion Adjuvant

Nasal administration of an oil-in-water nanoemulsion (NE) adjuvant W(80)5EC produces potent systemic and mucosal, Th-1– and Th-17–balanced cellular responses. However, its molecular mechanism of action has not been fully characterized and is of particular interest because NE does not contain specifi...

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Bibliographische Detailangaben
Hauptverfasser: Bielinska, Anna U., Makidon, Paul E., Janczak, Katarzyna W., Blanco, Luz P., Swanson, Benjamin, Smith, Douglas M., Pham, Tiffany, Szabo, Zsuzsanna, Kukowska-Latallo, Jolanta F., Baker, James R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: AAI 2014
Schlagworte:
Immunotherapy and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948110/
https://ncbi.nlm.nih.gov/pubmed/24532579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301424
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