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Nanoemulsion mucosal adjuvant uniquely activates cytokine production by nasal ciliated epithelium and induces dendritic cells trafficking

While the nasal mucosa is a potentially useful site for human immunization, toxin-based nasal adjuvants are generally unsafe and less effective in humans. Safe mucosal adjuvants that activate protective immunity via mucosal administration are highly dependent on barrier antigen sampling by epithelia...

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Autors principals: Makidon, Paul E., Belyakov, Igor M., Janczak, Katarzyna W., Landers, Jeffrey, Bielinska, Anna U., Groom, Jeffrey V., Baker, James R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929939/
https://ncbi.nlm.nih.gov/pubmed/22653620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142346
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