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Scar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in 3D
The Scar/WAVE complex plays a major role in the motility of cells by activating the Arp2/3 complex, which initiates actin branching and drives protrusions. Mammals have three Scar/WAVE isoforms, which show some tissue specific expression, but their functions have not been differentiated. Here we sho...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929901/ https://ncbi.nlm.nih.gov/pubmed/22909346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20112206 |
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