N-Acetyl-Serotonin Offers Neuroprotection through Inhibiting Mitochondrial Death Pathways and Autophagic Activation in Experimental Models of Ischemic Injury

N-acetylserotonin (NAS) is an immediate precursor of melatonin, which we have reported is neuroprotective against ischemic injury. Here we test whether NAS is a potential neuroprotective agent in experimental models of ischemic injury. We demonstrate that NAS inhibits cell death induced by oxygen–gl...

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Detalhes bibliográficos
Main Authors: Zhou, Hua, Wang, Jian, Jiang, Jiying, Stavrovskaya, Irina G., Li, Mingchang, Li, Wei, Wu, Qiaofeng, Zhang, Xinmu, Luo, Chengliang, Zhou, Shuanhu, Sirianni, Ana C., Sarkar, Sovan, Kristal, Bruce S., Friedlander, Robert M., Wang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929763/
https://ncbi.nlm.nih.gov/pubmed/24553937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1948-13.2014
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