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N-acetyl serotonin derivatives as potent neuroprotectants for retinas
N-acetylserotonin (NAS) is synthesized from serotonin by arylalkylamine N-acetyltransferase (AANAT), which is predominantly expressed in the pineal gland and retina. NAS activates TrkB in a circadian manner and exhibits antidepressant effects in a TrkB-dependent manner. It also enhances neurogenesis...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295250/ https://ncbi.nlm.nih.gov/pubmed/22331903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119201109 |
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