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N-acetyl serotonin derivatives as potent neuroprotectants for retinas

N-acetylserotonin (NAS) is synthesized from serotonin by arylalkylamine N-acetyltransferase (AANAT), which is predominantly expressed in the pineal gland and retina. NAS activates TrkB in a circadian manner and exhibits antidepressant effects in a TrkB-dependent manner. It also enhances neurogenesis...

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Bibliografski detalji
Glavni autori: Shen, Jianying, Ghai, Kanika, Sompol, Pradoldej, Liu, Xia, Cao, Xuebing, Iuvone, P. Michael, Ye, Keqiang
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295250/
https://ncbi.nlm.nih.gov/pubmed/22331903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119201109
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