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Catabolism of 2-deoxyglucose by phagocytic leukocytes in the presence of 12-O-tetradecanoyl phorbol-13-acetate.

We have found that phagocytic leukocytes exposed to the tumor-promoting agent, 12-O-tetradecanoyl phorbol-13-acetate, efficiently release carbon-1 of 2-deoxyglucose in the form of CO2 with concurrent intracellular accumulation of a phosphorylated 5-carbon intermediate. In the absence of 12-O-tetrade...

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Main Authors: Zabos, P, Kyner, D, Mendelsohn, N, Schreiber, C, Waxman, S, Christman, J, Acs, G
格式: Artigo
語言:Inglês
出版: 1978
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC392976/
https://ncbi.nlm.nih.gov/pubmed/310120
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