Catabolism of 2-deoxyglucose by phagocytic leukocytes in the presence of 12-O-tetradecanoyl phorbol-13-acetate.

We have found that phagocytic leukocytes exposed to the tumor-promoting agent, 12-O-tetradecanoyl phorbol-13-acetate, efficiently release carbon-1 of 2-deoxyglucose in the form of CO2 with concurrent intracellular accumulation of a phosphorylated 5-carbon intermediate. In the absence of 12-O-tetrade...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Zabos, P, Kyner, D, Mendelsohn, N, Schreiber, C, Waxman, S, Christman, J, Acs, G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1978
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/310120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.11.5422
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