12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region.

Genomic clones coding for human fibroblast collagenase were isolated. By constructing and transfecting mutants with 5' and 3' deletion mutations of the 5' control region of the gene into human or murine cells, we delimited a 32-base-pair sequence at positions -73 to -42 which is requi...

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Bibliographic Details
Main Authors: Angel, P, Baumann, I, Stein, B, Delius, H, Rahmsdorf, H J, Herrlich, P
Format: Artigo
Language:Inglês
Published: 1987
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC365350/
https://ncbi.nlm.nih.gov/pubmed/3037355
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