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An AP1-binding site in the c-fos gene can mediate induction by epidermal growth factor and 12-O-tetradecanoyl phorbol-13-acetate.

We have demonstrated that two sequence elements in the c-fos promoter can mediate the response of the gene to epidermal growth factor and the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate (TPA). The first is the previously described serum response element. The second is a sequence element hig...

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Dettagli Bibliografici
Autori principali: Fisch, T M, Prywes, R, Roeder, R G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC362726/
https://ncbi.nlm.nih.gov/pubmed/2498646
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