Leptin Acts Independently of Food Intake to Modulate Gut Microbial Composition in Male Mice

Shifts in the composition of gut bacterial populations can alter host metabolism and may contribute to the pathogenesis of metabolic disorders, including obesity. Mice deficient in leptin action are obese with altered microbiota and increased susceptibility to certain intestinal pathogens. Because a...

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Hauptverfasser: Rajala, Michael W., Patterson, Christa M., Opp, Judith S., Foltin, Susan K., Young, Vincent B., Myers, Martin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2014
Schlagworte:
Diabetes-Insulin-Glucagon-Gastrointestinal
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929727/
https://ncbi.nlm.nih.gov/pubmed/24424041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1085
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