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Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development

The bone morphogenetic protein (BMP) signaling pathways have important roles in embryonic development and cellular homeostasis, with aberrant BMP signaling resulting in a broad spectrum of human disease. We report that BMPs unexpectedly signal through the canonical transforming growth factor β (TGF-...

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Detalhes bibliográficos
Main Authors: Holtzhausen, Alisha, Golzio, Christelle, How, Tam, Lee, Yong-Hun, Schiemann, William P., Katsanis, Nicholas, Blobe, Gerard C.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929667/
https://ncbi.nlm.nih.gov/pubmed/24308972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-239178
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