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Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells
Both the transforming growth factor β (TGF-β) and integrin signalling pathways have well-established roles in angiogenesis. However, how these pathways integrate to regulate angiogenesis is unknown. Here, we show that the extracellular matrix component, fibronectin, and its cellular receptor, α5β1 i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463850/ https://ncbi.nlm.nih.gov/pubmed/22940691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.246 |
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