Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

The development of efficient strategies for generating fully human monoclonal antibodies with unique functional properties that are exploitable for tailored therapeutic interventions remains a major challenge in the antibody technology field. Here, we present a methodology for recovering such antibo...

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Main Authors: Diebolder, Philipp, Keller, Armin, Haase, Stephanie, Schlegelmilch, Anne, Kiefer, Jonathan D, Karimi, Tamana, Weber, Tobias, Moldenhauer, Gerhard, Kehm, Roland, Eis-Hübinger, Anna M, Jäger, Dirk, Federspil, Philippe A, Herold-Mende, Christel, Dyckhoff, Gerhard, Kontermann, Roland E, Arndt, Michaela AE, Krauss, Jürgen
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929437/
https://ncbi.nlm.nih.gov/pubmed/24256717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27236
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