Impact of Valency of a Glycoprotein B-Specific Monoclonal Antibody on Neutralization of Herpes Simplex Virus

Herpes simplex virus (HSV) glycoprotein B (gB) is an integral part of the multicomponent fusion system required for virus entry and cell-cell fusion. Here we investigated the mechanism of viral neutralization by the monoclonal antibody (MAb) 2c, which specifically recognizes the gB of HSV type 1 (HS...

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Hauptverfasser: Krawczyk, Adalbert, Krauss, Jürgen, Eis-Hübinger, Anna M., Däumer, Martin P., Schwarzenbacher, Robert, Dittmer, Ulf, Schneweis, Karl E., Jäger, Dirk, Roggendorf, Michael, Arndt, Michaela A. E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028897/
https://ncbi.nlm.nih.gov/pubmed/21123390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01924-10
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