Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

The development of efficient strategies for generating fully human monoclonal antibodies with unique functional properties that are exploitable for tailored therapeutic interventions remains a major challenge in the antibody technology field. Here, we present a methodology for recovering such antibo...

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Main Authors: Diebolder, Philipp, Keller, Armin, Haase, Stephanie, Schlegelmilch, Anne, Kiefer, Jonathan D, Karimi, Tamana, Weber, Tobias, Moldenhauer, Gerhard, Kehm, Roland, Eis-Hübinger, Anna M, Jäger, Dirk, Federspil, Philippe A, Herold-Mende, Christel, Dyckhoff, Gerhard, Kontermann, Roland E, Arndt, Michaela AE, Krauss, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929437/
https://ncbi.nlm.nih.gov/pubmed/24256717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27236
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