Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst

The transcription factor Oct4 is required in vitro for establishment and maintenance of embryonic stem cells and for reprogramming somatic cells to pluripotency. In vivo, it prevents the ectopic differentiation of early embryos into trophoblast. Here, we further explore the role of Oct4 in blastocys...

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Detalles Bibliográficos
Autores principales: Le Bin, Gloryn Chia, Muñoz-Descalzo, Silvia, Kurowski, Agata, Leitch, Harry, Lou, Xinghua, Mansfield, William, Etienne-Dumeau, Charles, Grabole, Nils, Mulas, Carla, Niwa, Hitoshi, Hadjantonakis, Anna-Katerina, Nichols, Jennifer
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2014
Materias:
Stem Cells and Regeneration
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929414/
https://ncbi.nlm.nih.gov/pubmed/24504341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.096875
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