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Absence of cell surface expression of human ACE leads to perinatal death
Renal tubular dysgenesis (RTD) is a recessive autosomal disease characterized most often by perinatal death. It is due to the inactivation of any of the major genes of the renin-angiotensin system (RAS), one of which is the angiotensin I-converting enzyme (ACE). ACE is present as a tissue-bound enzy...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929087/ https://ncbi.nlm.nih.gov/pubmed/24163131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt535 |
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