The absence of intrarenal ACE protects against hypertension

Activation of the intrarenal renin-angiotensin system (RAS) can elicit hypertension independently from the systemic RAS. However, the precise mechanisms by which intrarenal Ang II increases blood pressure have never been identified. To this end, we studied the responses of mice specifically lacking...

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Main Authors: Gonzalez-Villalobos, Romer A., Janjoulia, Tea, Fletcher, Nicholas K., Giani, Jorge F., Nguyen, Mien T.X., Riquier-Brison, Anne D., Seth, Dale M., Fuchs, Sebastien, Eladari, Dominique, Picard, Nicolas, Bachmann, Sebastian, Delpire, Eric, Peti-Peterdi, Janos, Navar, L. Gabriel, Bernstein, Kenneth E., McDonough, Alicia A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638907/
https://ncbi.nlm.nih.gov/pubmed/23619363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65460
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