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Evidence for Phenylalanine Zipper-Mediated Dimerization in the X-Ray Crystal Structure of a Magainin 2 Analogue

High-resolution structure elucidation has been challenging for the large group of host-defense peptides that form helices on or within membranes but do not manifest a strong folding propensity in aqueous solution. Here we report the crystal structure of an analogue of the widely-studied host-defense...

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Main Authors: Hayouka, Zvi, Mortenson, David E., Kreitler, Dale F., Weisblum, Bernard, Forest, Katrina T., Gellman, Samuel H.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928869/
https://ncbi.nlm.nih.gov/pubmed/24102563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja409082w
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