Assessment of the In vivo Antitumor Effects of ENMD-2076, a Novel Multitargeted Kinase Inhibitor, against Primary and Cell Line–Derived Human Colorectal Cancer Xenograft Models

PURPOSE: This in vivo study was designed to investigate the efficacy of ENMD-2076, a small-molecule kinase inhibitor with activity against the Aurora kinases A and B, and several other tyrosine kinases linked to cancer, including vascular endothelial growth factor receptor 2, cKit, and fibroblast gr...

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Detalhes bibliográficos
Main Authors: Tentler, John J., Bradshaw-Pierce, Erica L., Serkova, Natalie J., Hasebroock, Kendra M., Pitts, Todd M., Diamond, Jennifer R., Fletcher, Graham C., Bray, Mark R., Eckhardt, S. Gail
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928713/
https://ncbi.nlm.nih.gov/pubmed/20406842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0325
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