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GLI1 upregulates C-JUN through a specific 130-kDa isoform
The Hedgehog pathway is molecularly linked to increased resistance to cisplatin and increased repair of platinum-DNA damage, through C-JUN. GLI1, which has five known isoforms, is a positive transcriptional regulator in Hedgehog. Southwestern blot assay, EMSA and ChIP assays indicate that only one o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928471/ https://ncbi.nlm.nih.gov/pubmed/24366538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.2222 |
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