GLI1 upregulates C-JUN through a specific 130-kDa isoform

The Hedgehog pathway is molecularly linked to increased resistance to cisplatin and increased repair of platinum-DNA damage, through C-JUN. GLI1, which has five known isoforms, is a positive transcriptional regulator in Hedgehog. Southwestern blot assay, EMSA and ChIP assays indicate that only one o...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: AMABLE, LAUREN, GAVIN, ELAINE, KUDO, KENJI, MENG, ERHONG, ROCCONI, RODNEY P., SHEVDE, LALITA A., REED, EDDIE
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2013
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928471/
https://ncbi.nlm.nih.gov/pubmed/24366538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.2222
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki