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Desmoglein 2 Depletion Leads to Increased Migration and Upregulation of the Chemoattractant Secretoneurin in Melanoma Cells

During development and progression of malignant melanoma, an important role has been attributed to alterations of cell-cell adhesions, in particular, to a “cadherin switch” from E- to N-cadherin. We have previously shown that a subtype of melanoma cells express the desmosomal cadherin desmoglein 2 a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Peitsch, Wiebke K., Doerflinger, Yvette, Fischer-Colbrie, Reiner, Huck, Volker, Bauer, Alexander T., Utikal, Jochen, Goerdt, Sergij, Schneider, Stefan W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928442/
https://ncbi.nlm.nih.gov/pubmed/24558503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089491
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