Desmoglein 2 Depletion Leads to Increased Migration and Upregulation of the Chemoattractant Secretoneurin in Melanoma Cells

During development and progression of malignant melanoma, an important role has been attributed to alterations of cell-cell adhesions, in particular, to a “cadherin switch” from E- to N-cadherin. We have previously shown that a subtype of melanoma cells express the desmosomal cadherin desmoglein 2 a...

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Main Authors: Peitsch, Wiebke K., Doerflinger, Yvette, Fischer-Colbrie, Reiner, Huck, Volker, Bauer, Alexander T., Utikal, Jochen, Goerdt, Sergij, Schneider, Stefan W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928442/
https://ncbi.nlm.nih.gov/pubmed/24558503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089491
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