Desmoglein 2 Depletion Leads to Increased Migration and Upregulation of the Chemoattractant Secretoneurin in Melanoma Cells

During development and progression of malignant melanoma, an important role has been attributed to alterations of cell-cell adhesions, in particular, to a “cadherin switch” from E- to N-cadherin. We have previously shown that a subtype of melanoma cells express the desmosomal cadherin desmoglein 2 a...

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Detalhes bibliográficos
Main Authors: Peitsch, Wiebke K., Doerflinger, Yvette, Fischer-Colbrie, Reiner, Huck, Volker, Bauer, Alexander T., Utikal, Jochen, Goerdt, Sergij, Schneider, Stefan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928442/
https://ncbi.nlm.nih.gov/pubmed/24558503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089491
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