A rationale for stabilization of oxygen-labile enzymes: application to a clostridial hydrogenase.
A general procedure for stabilization of O2-labile enzymes exploiting "salting out" of oxygen from the microenvironment in the molecular layers immediately adjacent to charged surfaces of polyionic solid adsorbents has been developed. Empirical verification of this rationale is provided. The half-li...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392841/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/278979/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.8.3640 |
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