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Long-Term Activation upon Brief Exposure to Xanomleline Is Unique to M(1) and M(4) Subtypes of Muscarinic Acetylcholine Receptors
Xanomeline is an agonist endowed with functional preference for M(1)/M(4) muscarinic acetylcholine receptors. It also exhibits both reversible and wash-resistant binding to and activation of these receptors. So far the mechanisms of xanomeline selectivity remain unknown. To address this question we...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928307/ https://ncbi.nlm.nih.gov/pubmed/24558448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088910 |
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