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Noisy silence: Non-coding RNA and heterochromatin formation at repetitive elements

A significant fraction of eukaryotic genomes comprises repetitive sequences, including rRNA genes, centromeres, telomeres, and retrotransposons. Repetitive elements are hotspots for recombination and represent a serious challenge for genome integrity. Maintaining these repeated elements in a compact...

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Hlavní autoři: Bierhoff, Holger, Postepska-Igielska, Anna, Grummt, Ingrid
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928186/
https://ncbi.nlm.nih.gov/pubmed/24121539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.26485
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