Chargement en cours...
lncRNA KHPS1 Activates a Poised Enhancer by Triplex-Dependent Recruitment of Epigenomic Regulators
Summary: Transcription of the proto-oncogene SPHK1 is regulated by KHPS1, an antisense RNA that activates SPHK1 expression by forming a triple-helical RNA-DNA-DNA structure at the SPHK1 enhancer. Triplex-mediated tethering of KHPS1 to its target gene is required for recruitment of E2F1 and p300 and...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2019-03-01
|
| Collection: | Cell Reports |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S2211124719302384 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|