Indirubin-3′-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration

AIMS: The small molecule indirubin-3′-monoxime (I3MO) has been shown to inhibit vascular smooth muscle cell (VSMC) proliferation and neointima formation in vivo. The influence of I3MO on VSMC migration and vascular inflammation, two additional key players during the onset of atherosclerosis and rest...

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Détails bibliographiques
Auteurs principaux: Blažević, Tina, Schaible, Anja M., Weinhäupl, Katharina, Schachner, Daniel, Nikels, Felix, Weinigel, Christina, Barz, Dagmar, Atanasov, Atanas G., Pergola, Carlo, Werz, Oliver, Dirsch, Verena M., Heiss, Elke H.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928003/
https://ncbi.nlm.nih.gov/pubmed/24368834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt339
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