Indirubin-3′-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration

AIMS: The small molecule indirubin-3′-monoxime (I3MO) has been shown to inhibit vascular smooth muscle cell (VSMC) proliferation and neointima formation in vivo. The influence of I3MO on VSMC migration and vascular inflammation, two additional key players during the onset of atherosclerosis and rest...

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Autors principals: Blažević, Tina, Schaible, Anja M., Weinhäupl, Katharina, Schachner, Daniel, Nikels, Felix, Weinigel, Christina, Barz, Dagmar, Atanasov, Atanas G., Pergola, Carlo, Werz, Oliver, Dirsch, Verena M., Heiss, Elke H.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928003/
https://ncbi.nlm.nih.gov/pubmed/24368834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt339
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