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Indirubin-3′-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration

AIMS: The small molecule indirubin-3′-monoxime (I3MO) has been shown to inhibit vascular smooth muscle cell (VSMC) proliferation and neointima formation in vivo. The influence of I3MO on VSMC migration and vascular inflammation, two additional key players during the onset of atherosclerosis and rest...

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Bibliografiska uppgifter
Huvudupphovsmän: Blažević, Tina, Schaible, Anja M., Weinhäupl, Katharina, Schachner, Daniel, Nikels, Felix, Weinigel, Christina, Barz, Dagmar, Atanasov, Atanas G., Pergola, Carlo, Werz, Oliver, Dirsch, Verena M., Heiss, Elke H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928003/
https://ncbi.nlm.nih.gov/pubmed/24368834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt339
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